A postdoctoral position is available in Dr. Emmanuel Zorn’s lab at the Columbia Center for Translational Immunology (CCTI) to study the mechanisms underlying chronic rejection after human kidney transplantation. The research will primarily examine the role of graft-infiltrating immune cells and circulating graft-reactive antibodies in different subtypes of rejection. The project will leverage well-characterized human transplant specimens and clinical samples to identify mechanisms, biomarkers, and potential therapeutic targets that could improve the diagnosis, monitoring, and treatment of chronic kidney allograft rejection. This NIH-funded study provides a unique opportunity to engage in patient-focused translational research at a premier transplant center and contribute to improving clinical outcomes. Experimental approaches will include primary human cell culture, ELISA, ELISPOT, protein assays, RNA-seq, single-cell genomic approaches, and functional cell-based assays. The applicant will also be involved in collaborative projects across the CCTI. The CCTI is a multidisciplinary research center with affiliations across multiple departments and research centers at Columbia University Irving Medical Center.
We are seeking a creative, independent and driven individual with documented research experience related to this position. The candidate should have a recent PhD in Immunology, Molecular Medicine, or a related field, with a proven track record of productivity (at least one first-author publication in a peer-reviewed journal is expected). In addition, the successful candidate will demonstrate creativity, a strong work ethic, motivation, the ability to manage multiple projects, and the ability to work effectively in a highly collaborative research environment, as well as excellent written and verbal communication skills. Familiarity with flow cytometry, in vitro immunoassays, gene expression analysis, and the isolation and culture of immune cells is highly desirable.
Columbia University Irving Medical Center, located in Upper Manhattan, is an equal opportunity employer and provides a world-class scientific environment for biomedical research and training.
Applicants should send a full CV, a one-page cover letter highlighting their research interests and career goals and the names and contact information for three references directly to the principal investigator:
ez2184@cumc.columbia.edu
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